By Gunhild Waldemar, Alistair Burns
A part of the Oxford Neurology Library sequence, this moment version of Alzheimer's Disease is a succinct and functional advent to the prognosis, evaluate and administration of Alzheimer's illness. This useful pocketbook comprises 14 absolutely up-to-date chapters on key issues akin to pathophysiology, epidemiology, pharmacological remedies, and mental signs. The advent of latest chapters on abnormal shows, end-of-life concerns, and case vignettes make sure the reader is totally outfitted with the newest knowing of the potential explanations of the sickness, equipment of prognosis, and administration innovations. content material is gifted in a concise and straightforward to learn layout designed for speedy reference, with worthwhile key issues indexed at first of every chapter.
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Spasticity and deformities are common. 7 Atypical clinical variants CHAPTER 4 Clinical with greater cognitive decline and faster progression. Recent evidence indicates that epileptic activity in the early stages of AD is more prevalent than previously recognized. Epileptiform activity usually occurs in the temporal lobes and cause transient cognitive symptoms that may be difficult to recognize as seizures. The routine electroencephalogram (EEG) usually shows normal findings and other techniques, such as long-term video EEG monitoring, may reveal abnormal activity.
25 Chapter 4 Clinical course of Alzheimer’s disease Alberto Lleó and Rafael Blesa Key points • Alzheimer’s disease is an age-related neurodegenerative disorder, with onset usually in late life, characterized by cognitive impairment, a variety of behavioural symptoms, and restrictions in the activities of daily living • The initial symptom is episodic memory loss, in particular in delayed recall of visual and/or verbal material. Introduction Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder characterized by cognitive impairment, a variety of neuropsychiatric symptoms, and restrictions in the activities of daily living.
International Journal of Geriatric Psychiatry 205;30:234–46. , and Winblad, B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurology 2004;3:343–53. of Alzheimer’s disease CHAPTER 3 Epidemiology Fratiglioni L. and Qiu C. Epidemiology of dementia. In: T. Dening and A. Thomas (eds). The Oxford Textbook of Old Age Psychiatry. 2nd edn. New York, NY: Oxford University Press, 203, pp. 389–43. , et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomized controlled trial.
Alzheimer's disease by Gunhild Waldemar, Alistair Burns